W. Lance George, M.D.
Attending Physician, Infectious Diseases, VA Greater Los Angeles Healthcare System
Chief, Hospitalist Division, VA Greater Los Angeles Healthcare System
Associate Chair, Department of Medicine, VA Greater Los Angeles Healthcare System
Professor of Medicine, The David Geffen School of Medicine at UCLA



Department of Medicine (111)
11301 Wilshire Blvd.
VA Greater Los Angeles Healthcare System
Los Angeles, CA 90073
Tel: 310-268-3125
William.George@va.gov

Research and Clinical Interests:
Clostridium difficile and selected other enteric pathogens
Medical microbiology
Selected aspects of HIV infection
Infective endocarditis
Viral infections of the liver

Selected Publications:

1.     George, W.L., Sutter, V.L., Goldstein, E.J.C., Ludwig, S.L., and S.M Finegold.  Aetiology of antimicrobial agent-associated-colitis.  Lancet i:802-803, 1978.

2.     George, W.L., Sutter, V.L., Citron, D., and S.M. Finegold.  Selective and differential medium for isolation of Clostridium difficile.  J. Clin. Micro. 9:214-219, 1979.

3.     George, W.L., Kirby, B.D., Sutter, V.L., and S.M. Finegold.  Antimicrobial susceptibility of Clostridium difficile.  In: D. Schlessinger (ed.) Microbiology - 1979, American Society for Microbiology, 1979, Washington, DC, p. 267-271.

4.     George, W.L., Volpicelli, N., Stiner, D.B., Richman, D.D., Liechty, E.J., Mok, H.Y.I., Rolfe, R.D., and S.M. Finegold.  Relapse of pseudomembranous colitis after vancomycin therapy.  N. Engl. J. Med. 301:414-415, 1979.

5.     Mulligan, M.E., Rolfe, R.D., Finegold, S.M., and W.L. George.  Contamination of a hospital environment by Clostridium difficile.  Curr. Microbiol.  3:173-175, 1980.

6.     George, W.L., Kirby, B.D., Sutter, V.L., Wheeler, L.A., Mulligan, M.E., and S.M. Finegold.  Intravenous metronidazole for treatment of infections involving anaerobic bacteria.  Antimicrob. Agents Chemother. 21:441-449, 1982.

7.     George, W.L., Nakata, M.M., Thompson, J., and M.L. White.  Aeromonas-related diarrhea in adults.  Arch. Intern. Med. 145:2207-2211, 1985.

8.     Reinhardt, J.F., and W.L. George.  Comparative in vitro activities of selected antimicrobial agents against Aeromonas species and Plesiomonas shigelloides.  Antimicrob. Agents Chemother.  27:643-645, 1985.

9.     Reinhardt, J.F., and W.L. George.  Plesiomonas shigelloides-associated diarrhea.  J.A.M.A.  253:3294-3295, 1985.

10.  Jones, M.J., Miller, J.N., and W.L. George.  Microbiological characterization of spirochetes isolated from the feces of homosexual males.  J. Clin. Microbiol.  24:1071-1074, 1986.

11.  Muller, E.L., Pitt, H.A., and W.L. George.  Prairie dog model for anti-microbial agent-induced Clostridium difficile diarrhea.  Infect. Immun. 55:198-200, 1987.

12.  Statner, B., and W.L. George.  Congo Red uptake by Aeromonas species.  J. Clin. Microbiol.  25:876-878, 1987.

13.  Gardner, S.E., Fowlston, S.E., and W.L. George.  In vitro production of cholera toxin-like activity by Plesiomonas shigelloides.  J. Infect. Dis.  156:720-722, 1987.

14.  Ruane, P.J., Nakata, M.M., Reinhardt, J.F. and W.L. George.  Spirochete-like organisms in the human gastrointestinal tract.  Rev. Infect. Dis.  11:184-196, 1989.

15.  Gardner, S.E., Fowlston, S.E. and W.L. George.  Effect of iron on production of a possible virulence factor by Plesiomonas shigelloides.  J. Clin. Microbiol.  28:811-813, 1990.

16.  Hamilton, J.D., Hartigan, P.M., Simberkoff, M.S., Day, P.L., Diamond, G.R., Dickinson, G.M., Drusano, G.L., Egorin, M.J., George, W.L., Gordin, F.L., Hawkes, C.A., Jensen, P.J., Klimas, N.J., Labriola, A.M., Lahart, C.J., O'Brien, W.A., Oster, C.N., Weinhold, K.J., Wray, N.P., Zolla-Pazner, S.B., and the VA Cooperative Study Group on AIDS Treatment.  A controlled trial of early versus late treatment with zidovudine in symptomatic human immunodeficiency virus infection:  Results of the VA cooperative study. N. Engl. J. Med. 326:437-443, 1992.

17.  Simberkoff, M.S., Hartigan, P.M., Hamilton, J.D., Day, P.L., Diamond, G.R., Dickinson, G.M., Drusano, G.L., Egorin, M.J., George, W.L., Gordin, F.L., Hawkes, C.A., Jensen, P.J., Klimas, N.J., Labriola, A.M., Lahart, C.J., O'Brien, W.A., Oster, C.N., Weinhold, K.J., Wray, N.P., Zolla-Pazner, S.B., and the VA Cooperative Study Group on AIDS Treatment.  Long-term follow-up of symptomatic HIV-infected patients originally randomized to early versus later zidovudine treatment: Report of a VA cooperative study. J. Acquired Imm. Def. Synd. & Hum. Retrovirol.  11:142-50, 1996.

18.  Cunningham, W.E., Shapiro, M.F., Hays, R.D., Dixon, W.J., Visscher, B.R., George, W.L., Ettl, M.K., and Beck, C.K. Constitutional symptoms and health-related quality of life in patients with symptomatic HIV disease.  Am.  J.  Med. 104:129-36, 1998.

19.  Rabeneck, L., Menke, T., Simberkoff, M.S., Hartigan, P.M., Dickinson, G.M., Jensen, P.C., George, W.L., Goetz, M.B., and N.P. Wray.  Using the national registry of HIV-infected veterans in research:  Lessons for the development of disease registries.  J. Clin. Epidemiol.  54:1195-1203, 2001.

20.  George, W.L.  Infectious Complications.  Chapter 35, In:  Manual of Clinical Oncology, 5th ed;  D.A. Casciato (ed.).  Lippincott Williams & Wilkins, Philadelphia, p 657-682, 2004.

21.  Fujitani, S., Rowlinson, M.C., and George, W.L. Penicillin G-resistant viridans group streptococcal endocarditis and interpretation of the American Heart Association's Guidelines for the Treatment of Infective Endocarditis. Clin. Infect. Dis. 46:1064-6, 2008.

 

2008